Annulus Rheumaticus (AR) is an excessive accumulation of uric acid within your cells —not in your blood— that inflames, get sick or destroys a tissue or organ if it is not controlled properly and in time. AR are involved in severe illnesses like arthritis, cancer, liver cirrhosis, depression, diabetes, cardiomegaly, lupus, migraines, obesity, prostatitis, irritable bowel syndrome, varicose veins among others.